About Research Team
Dr. Stephen Freedland will have overall responsibility for its organization and operation as a contact PI, which includes: conduct, completion and reporting of the research products; optimal functioning of the administrative staffs; and management of a synergistic relationship between this grant and other research grants relevant to IC. He is a NIH-funded urologist who has expertise in patient-oriented study in urologic research.
He is in an outstanding position within the CSMC as well as VA, with its resources of thousands of patients, to look for new opportunities to implement studies employing these scientific assets.
Dr. Stephen Freedland’s BIO
Dr. Jennifer Anger is an NIH-funded urologist who is board-certified in Female Pelvic Medicine and Reconstructive Surgery. She is the Associate Director of Urological Research at Cedars-Sinai Medical Center (CSMC) and CSMC Associate Professor of Surgery. In November of 2010 she moved to Cedars-Sinai from UCLA, where she holds a faculty appointment and close collaborations. Dr. Anger has expertise in complex multi-site surgical trials, and was lead PI on the Abdominal Colpopexy: Comparison of Endoscopic Surgical Strategies (ACCESS) Trial.
This study was funded by a challenge grant as part of the American Recovery and Reinvestment Act. Dr. Anger is co-PI with Dr. Kim of a recently funded R01 grant (R01DK100974) to study urine metabolites in UCPPS. Dr. Anger is the contact PI of the Cedars-Sinai Medical Center site for the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) project (U01 DK103260) and work closely in concert with Drs. Kim. Dr. Anger will be responsible for the clinical integrity of the study, participate in experimental design, data interpretation, writing manuscripts, oversight, and presentation of findings to the scientific and clinical communities.
Dr. Jennifer Anger’s BIO
Dr. Jayoung Kim is a translational scientist with extensive experience in benign urinary tract diseases, particularly IC, with a focus on molecular mechanisms and biomarker discovery. Using a mass spectrometry-based proteomics approach, she and Drs. Freeman and Yang (co-Investigators of this grant) have discovered an important signaling network related to UCPPS and reported their findings in Molecular and Cellular Proteomics, the highest impact proteomics journal. Dr. Kim, who was recently named as an IMAGINE NO IC Scholar, has been continuously funded by the Interstitial Cystitis Association (ICA) and by the Fishbein Family Foundation for the past 5 years to study IC.
Dr. Kim is PI of a recently funded R01 grant (R01DK100974) and U01 grant (U01 DK103260) to study the signature of IC. She will be responsible for the overall direction of this project, design and perform experiments, participate in data interpretation, present findings to the scientific community, provide progress reports to NIH, and write manuscripts. In this proposed study, she will be in charge of biomarker analysis and bioinformatics data analysis for validation for task.
Dr. Jayoung Kim’s BIO